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However, little is known about how an astrocyte functions in synapse formation, axon specification, neuroplasticity, neural homeostasis, neural network activity following dynamic surveillance, and CNS structure in neurological diseases

Reactive derivatives of oxygen, termed reactive oxygen species (ROS), are toxic for non-target molecules 2 , causing oxidative damage to nucleic acids, proteins and lipids 3 , reviewed by 4,5

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In parallel, to determine the effect of inulin supplementation on HFCS-elicited pathologies, we used an open-source diet, a control diet used in many nutritional studies 36,37,38 , and formulated an inulin-enriched diet by replacing a small portion of corn starch (10% w/w) with inulin, as in previous studies 39,40,41 (Supplementary Table 1)